Sequence variation at the 3′ end of the neuraminidase gene from 39 influenza type A viruses
Identifieur interne : 002652 ( Main/Exploration ); précédent : 002651; suivant : 002653Sequence variation at the 3′ end of the neuraminidase gene from 39 influenza type A viruses
Auteurs : J. Blok [Australie] ; G. M. Air [Australie]Source :
- Virology [ 0042-6822 ] ; 1982.
English descriptors
- Teeft :
- Academic press, Acid, Amino, Amino acid, Amino acid changes, Amino acid differences, Amino acid sequence, Amino acid sequence changes, Amino acid sequences, Amino acids, Antigenic, Antigenic drift, Antigenic variation, Avian, Blok, Cdna, Clove, Coding triplet, Codon, Complete strain designations, Deletion, Gene, Genetic variation, Hemagglutinin, Hlnl, Hong kong, Hong kong virus, Human influenza virus, Immunological techniques, Influenza, Influenza type, Influenza virus, Influenza virus strains, Influenza viruses, Insertion, Kilbourne, Laver, Mutation, Neuraminidase, Neuraminidase gene, Neuraminidase genes, Neuraminidases, Nucleotide, Nucleotide changes, Nucleotide differences, Nucleotide sequence, Nucleotide sequences, Other strains, Peptide, Point mutations, Primer, Schild, Sequence data, Sequence differences, Sequence variation, Sequencing, Shope, Single base change, Subtype, Subtypes, Toby, Triplet, Unlabeled dodecamer, Viral, Virology, Virus, Virus strains.
Abstract
Abstract: Thirty-nine influenza virus strains belonging to eight serologically distinct neuraminidase subtypes (N1 to N8) were examined in order to study the genetic variation which occurs within a subtype of influenza neuraminidase. RNA segment 6, which codes for neuraminidase, was sequenced from the 3′ end using the dideoxy method. The sequences obtained for the different subtypes reveal that there are several kinds of variation: (a) point mutations in the RNA which sometimes change the amino acid sequence, (b) short regions of many nucleotide and amino acid changes, (c) small insertions and/or deletions (usually three nucleotides or one amino acid at a time), and (d) large deletions (from 33 to 48 nucleotides in length).
Url:
DOI: 10.1016/0042-6822(82)90162-3
Affiliations:
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RNA segment 6, which codes for neuraminidase, was sequenced from the 3′ end using the dideoxy method. The sequences obtained for the different subtypes reveal that there are several kinds of variation: (a) point mutations in the RNA which sometimes change the amino acid sequence, (b) short regions of many nucleotide and amino acid changes, (c) small insertions and/or deletions (usually three nucleotides or one amino acid at a time), and (d) large deletions (from 33 to 48 nucleotides in length).</div></front></TEI><affiliations><list><country><li>Australie</li></country></list><tree><country name="Australie"><noRegion><name sortKey="Blok, J" sort="Blok, J" uniqKey="Blok J" first="J." last="Blok">J. Blok</name></noRegion><name sortKey="Air, G M" sort="Air, G M" uniqKey="Air G" first="G. M." last="Air">G. M. Air</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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